6400 Series Triple Quadrupole LC/MS

Mass Spectrometry

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Choose an Agilent 6420, 6460, or 6495 Triple Quadrupole LC/MS System for unmatched productivity, performance, and value for all your analytical needs. The 6420 is economical and easy to use – a perfect workhorse instrument for laboratories requiring standard quantitative capabilities. The 6460 adds Agilent Jet Stream (AJS) technology to dramatically increase sensitivity for a wide range of challenging applications. Built on the proven performance of Agilent’s iFunnel Technology, the 6495 incorporates innovative ion optics and detector design for ultra-trace analysis – with low attogram limits of quantitation, excellent assay precision and accuracy, and wide dynamic range for your most demanding assays.

  • Achieve the highest sensitivity and precision – Agilent iFunnel Technology, the new ion optics and detector design in the 6495 dramatically increase ion sampling, transmission and detection, enabling the highest peak area response, excellent  peak area precision, and the lowest limits of detection and quantitation.
  • Screen, confirm and quantify – Triggered MRM (tMRM) combines fast and sensitive MRM quantitation with the generation of a product ion spectrum for library searching and compound screening and confirmation.
  • Automate compound optimization – MassHunter Optimizer software enables automated determination of compound MRM parameters in addition to source and iFunnel conditions.
  • Fast MRM acquisition speeds and ion polarity switching – An innovative collision cell eliminates cross-talk and enables 1ms MRM dwell times, together with fast polarity switching, ensures compatibility with UHPLC analyses.
  • Streamline method development – Dynamic MRM (dMRM) simplifies method development and allows thousands of compounds to be quantified in a single method with optimal sensitivity and reproducibility.
  • Compatibility with a wide range of ionization sources – ESI, AJS, APCI, APPI, Multi-mode sources, and innovative HPLC-Chip technology for robust and ultra-sensitive quantitation with small sample volumes.
  • Comprehensive and easy-to-use MassHunter Workstation software dramatically enhances productivity from method optimization, data acquisition to data processing and reporting.
  • Ordering Details

EPA Method 540: Selected Organic Contaminants Using Agilent Plexa CartridgesThis Application Note describes the analysis of 17 target organic contaminants per EPA Method 540 using the Agilent Infinity II 1290 HPLC and Model 6460 LC/MS/MS.
Found In : Application | Date: Mar 10, 2015 | FileSize: 0.196 MB
Simultaneous Determination of 21 Plant Growth Regulators in Various FruitsA method for simultaneous determination of 21 plant growth regulators in fruits has been developed based on QQQ6460 LCMS platform with high sensitivity and accuracy.
Found In : Application | Date: Feb 25, 2015 | FileSize: 0.250 MB
Highly Sensitive Detection of Pharmaceuticals and Personal Care Products (PPCPs) in Water Using an Agilent 6495 Triple Quadrupole Mass SpectrometerPrecise and accurate quantitation of 118 PPCPs in water was accomplished at part per trillion (ppt) levels using a 6495 QQQ LC/MS coupled to a 1290 Infinity System.
Found In : Application | Date: Jan 23, 2015 | FileSize: 1.481 MB
Ultrafast Quantitation of Fat Soluble Vitamins A and E in Human Serum Using the Agilent RapidFire High-Throughput Mass Spectrometry SystemRapidFire/MS/MS is capable of analyzing vitamins A and E in serum at 15 seconds/sample with comparable analytical results to LC/MS.
Found In : Application | Date: Nov 12, 2014 | FileSize: 0.715 MB
Solid Phase Extraction of Organophosphorus Pesticides in Water with Agilent Bond Elut PPLA full workflow solution to extract organophosphates in water used Bond Elut PPL for extraction and Agilent LC/MS/MS for separation with sensitivity and selectivity.
Found In : Application | Date: Nov 10, 2014 | FileSize: 0.100 MB
A Validated LC/MS/MS Solution for the Analysis of Pesticides and Other Chemical in Applesa Validated lC/Ms/Ms solution for the analysis of PestiCides and other CheMiCals in aPPles
Found In : Application | Date: Nov 05, 2014 | FileSize: 1.519 MB
Ultrafast Histone Deacetylase Selectivity Screening Using the Agilent RapidFire High-Throughput Mass Spectrometry SystemDescription of an ultrafast method for performing enzyme inhibition selectivity screening using the RapidFire SPE/MS/MS system.
Found In : Application | Date: Oct 22, 2014 | FileSize: 0.649 MB
Analysis of Pesticides by Superfluid Chromatography/Mass SpectrometryAn optimized Agilent 1260 Infinity Analytical SFC and 6460 Triple Quadrupole MS analyzed a 17-pesticide mix in 5 min with excellent separation and good peak shape.
Found In : Application | Date: Oct 15, 2014 | FileSize: 2.490 MB
Screening and Quantitation of 191 Mycotoxins and Other Fungal Metabolites in Almonds, Hazelnuts, Peanuts, and Pistachios Using UHPLC/MS/MSDevelopment and validation of a UHPLC/MS/MS method for the screening and quantitation of mycotoxins in nuts.
Found In : Application | Date: Sep 24, 2014 | FileSize: 0.433 MB
Found In : Application | Date: Sep 10, 2014 | FileSize: 0.554 MB

Agilent 6460 Triple Quadrupole LC/MS with Standard ESI SourceThe Agilent 6460 Triple Quadrupole LC/MS with standard ESI source (option 100) delivers superior sensitivity for trace level analysis.
Found In : Data Sheet | Date: Oct 23, 2014 | FileSize: 0.463 MB
Agilent 6490 Triple Quadrupole LC/MS with iFunnel TechnologyAgilent 6490 Triple Quadrupole LC/MS with iFunnel Technology
Found In : Data Sheet | Date: Mar 18, 2014 | FileSize: 0.093 MB
Agilent 6460 Triple Quadrupole LC/MS with Agilent Jet Stream Technology Data SheetThe 6460 Triple Quadrupole LC/MS, with Jet Stream Technology, achieves sensitivity and resolution specifications
Found In : Data Sheet | Date: Oct 15, 2008 | FileSize: 0.495 MB

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